Abstract: The establishment of Quaternary stratigraphic chronology framework is of great significance to the study of regional stratigraphic correlation and paleogeographic environment evolution. However, there are relatively few researches on Quaternary boreholes in northeast Songnen Plain, which poses challenges to accurately characterize regional Quaternary evolution. In order to establish the Quaternary stratigraphic framework in Suihua area, northeast Songnen Plain, by analyzing the color, structure and lithology combination characteristics of the core sediments of hole WKZK01, Wangkui County, Suihua City, Heilongjiang Province, the logging curve, C-M map, particle size parameter structure scattering map, particle size parameter characteristics, palynofossil association and OSL dating method were applied. Detailed stratigraphic division, sedimentary facies analysis and stratigraphic chronology framework establishment of hole WKZK01 in Wangkui County, Suihua City, Heilongjiang Province are carried out. The loose sediments revealed by hole WKZK01 in Wangkui County, Suihua City, Heilongjiang Province are divided into four sets of lithologic assemblage: the first set of lithologic assemblage represents Holocene black soil; The second set of lithologic assemblage represents the loess of Guxiangtun Formation with river biphasic characteristics. The third set of lithology association represents the loess deposited by aeolian facies in Harbin Formation. The fourth set of lithology association represents the loess of Huangshan Formation deposited by flu-lake facies. Based on the lithologic characteristics, grain size parameters, palynopalynite assemblages and OSL dating data, the Quaternary lithologic stratigraphy of Hole WKZK01 in Wangkui County, Suihua City, Heilongjiang Province is divided into Holocene Series, Guxiangtun Formation, Harbin Formation and Huangshan Formation with corresponding bottom boundary depths of 1.1m, 15.6m and 39.65m, respectively. The research results provide basic data for the Quaternary regional stratigraphic division and correlation study in this area.