Abstract: This paper reviews Li Siguang(J.S.Lee)'s thought on earthquake prediction and emphasizes the great significance of the view of following China's own road to carry out geostress observation and research and investigation of the active tectonic systems proposed by Li Siguang.According to the practice and experience in the work relating to earthquake prediction over the past 40 years,the paper further elucidates the idea that in the new situation we should make new supplements and developments of the thought and method.It is suggested that in the future,while we should continued to undertake earthquake prediction practice and sum up the experience,we should strengthen the study of the seismogenic mechanism.In addition,some concrete suggestions about how to carry out this research work is put forward.